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Nov 17, 2011 It is characterized by accumulation of clonal plasma cells, predominantly in the bone marrow. The prevalence of type 2 diabetes is increasing; therefore, it is expected that there will be an increase in the diagnosis of multiple myeloma with concomitant diabetes mellitus.
Jun 26, 2012 Objectives: Type 2 diabetes mellitus is present in approximately 10% of patients at diagnosis of multiple myeloma (MM) and is Key words type 2 diabetes mellitus; hyperglycaemia; hypoglycaemia; multiple myeloma; all-cause mortality nosis of type 2 diabetes was based on the criteria of the respective
We defined metformin users as patients with diabetes who were given metformin consistently for 4 years after their diabetes diagnosis and before multiple myeloma development, death, or censorship. Our primary outcome was time from MGUS diagnosis to multiple myeloma diagnosis. We used Kaplan-Meier curves and
Type 2 Diabetes (T2D) is a complex disease that is typically diagnosed in midlife and is characterized by progressive defects in insulin secretion and acti.
Aug 1, 2015 Type 2 diabetes-related variants influence the risk of developing multiple myeloma: results from the IMMEnSE consortium . 2012). The diagnosis of MM was assigned by physician and fulfilled the International Myeloma Working Group (IMWG) criteria (International Myeloma Working Group 2003). Controls
Jun 12, 2014 Background: Insulin/insulin-like growth factor-1 signalling may underlie the promoting effect of type 2 diabetes on cancer. This study examined the association of diabetes, including steroid-induced diabetes (SID), and the impact of anti-diabetic medication on clinical outcomes of multiple myeloma (MM).
It is characterized by accumulation of clonal plasma cells, predominantly in the bone marrow. The prevalence of type 2 diabetes is increasing; therefore, it is expected that there will be an increase in the diagnosis of multiple myeloma with concomitant diabetes mellitus.
e18564. Background: Dexamethasone is an effective drug in the treatment of Multiple Myeloma as a single agent and in combination with other drugs. In patients with diabetes mellitus, use of high dose dexamethasone may cause diabetes control difficult if not impossible. It was noted in our practice significant number of
Recently, metformin use in diabetic patients with multiple myeloma (MM) has been associated with improved overall survival (OS) (Wu et al, 2014). Additionally Patients who did not receive MM directed therapy within 6 months of diagnosis were excluded, as were patients who died within 1 year of MM diagnosis.
     

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